4/1/2023 0 Comments Pathological cyst![]() Some pseudocysts arise from the release of pancreatic enzymes into an anatomic sac. 7 The lesions develop when a focus of peripancreatic fat necrosis is resorbed, thereby producing a debris-filled space surrounded by granulation tissue that is ultimately enclosed within a fibrous capsule. Those resulting from biliary disease or trauma occur in younger patients and have an equal predilection for both sexes. They develop as a complication of alcoholic, biliary, or traumatic acute pancreatitis, 8, 9 predominantly in adult men. Pseudocysts are the most common type of cystic lesions of the pancreas, 7 although they rarely come to the attention of surgical pathologists because, often, they are managed medically or by surgical drainage without resection. Only rare nonmucinous cystic tumors that occur as a result of degenerative/necrotic changes in otherwise solid neoplasia, such as cystic ductal adenocarcinomas, cystic pancreatic endocrine neoplasia, and solid-pseudopapillary neoplasm, are also malignant and have variable degrees of aggressiveness. Those that are nonmucinous such as serous tumors, congenital cysts, lymphoepithelial cysts, and squamoid cyst of pancreatic ducts have no malignant potential. However, those that are mucinous, namely, intraductal papillary mucinous neoplasms and mucinous cystic neoplasms, constitute an important category because they have well-established malignant potential, representing an adenoma-carcinoma sequence. Objective.-To provide an overview of the current concepts in classification, differential diagnosis, and clinical/biologic behavior of pancreatic cystic tumors.ĭata Sources.-The authors' personal experience, based on institutional and consultation materials, combined with an analysis of the literature.Ĭonclusions.-In contrast to solid tumors, most of which are invasive ductal adenocarcinomas with dismal prognosis, cystic lesions of the pancreas are often either benign or low-grade indolent neoplasia. Consequently, in the past 2 decades, the nature of many cystic tumors in this organ has been better characterized, and significant developments have taken place in the classification and in our understanding of pancreatic cystic lesions. ![]() Context.-Cystic lesions of the pancreas are being recognized with increasing frequency and have become a more common finding in clinical practice because of the widespread use of advanced imaging modalities and the sharp drop in the mortality rate of pancreatic surgery. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |